H2AFX 抗体
Quick Overview for H2AFX 抗体 (ABIN7539773)
抗原
See all H2AFX 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- H2AFX Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human H2AFX expressed in E. Coli.
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亚型
- IgG1
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应用备注
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FCM: 1/200 - 1/400
ICC: 1/50 - 1/200
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限制
- 仅限研究用
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- H2AFX (H2A Histone Family, Member X (H2AFX))
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别名
- H2AFX
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背景
- Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.
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分子量
- 15.1 kDa
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UniProt
- P16104
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途径
- Telomere Maintenance, DNA Damage Repair, Positive Regulation of Response to DNA Damage Stimulus
抗原
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