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NOTCH2 抗体 (AA 1391-1677)

This anti-NOTCH2 antibody is a 小鼠 单克隆 antibody detecting NOTCH2 in ELISA, IHC, FACS 和 ICC. Suitable for 人.
产品编号 ABIN7539763
发货至: 中国

Quick Overview for NOTCH2 抗体 (AA 1391-1677) (ABIN7539763)

抗原

See all NOTCH2 抗体
NOTCH2 (Notch 2 (NOTCH2))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This NOTCH2 antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)

克隆位点

2D1B2
  • 抗原表位

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    AA 1391-1677

    原理

    NOTCH2 Antibody

    纯化方法

    Purified antibody

    免疫原

    Purified recombinant fragment of human NOTCH2 (AA: 1391-1677) expressed in E. Coli.

    亚型

    IgG2a
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/50 - 1/200

    限制

    仅限研究用
  • 缓冲液

    Purified antibody in PBS with 0.05 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • 抗原

    NOTCH2 (Notch 2 (NOTCH2))

    别名

    NOTCH2

    背景

    This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play a role in vascular, renal and hepatic development. Two transcript variants encoding different isoforms have been found for this gene.

    分子量

    265.4 kDa

    基因ID

    4853

    途径

    Notch Signaling, Stem Cell Maintenance
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