CD40 Ligand 抗体
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北京 101111
Quick Overview for CD40 Ligand 抗体 (ABIN7539620)
抗原
See all CD40 Ligand (CD40LG) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- AF/LE Purified Anti-Human CD154 Antibody [24-31]
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特异性
- Human
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纯化方法
- Protein A/G Purified
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内毒素水平
- Low Endotoxin: < 1.0 EU per mg of the antibody as determined by the LAL method.
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免疫原
- Recombinant Human CD154 protein
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亚型
- IgG1, kappa
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应用备注
- FCM:2 μg/mL(1x10^5-5x10^5 cells)
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- ≥ 1 mg/mL
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缓冲液
- Sterile PBS.
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
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- CD40 Ligand (CD40LG)
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别名
- CD154
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背景
- CD154 (CD40 ligand) is also known as CD40L, gp39, TRAP and T-BAM. CD40 ligand is a 32-39 kD type II transmembrane glycoprotein. It is a member of the TNF superfamily and is expressed on activated T cells. It has been reported to be important for B cell costimulation following binding of its receptor, CD40. Additionally, binding of CD40L to CD40 on B cells promotes the secretion of immunoglobulin and Ig isotype switching. CD40L is also involved in the regulation of cytokine production by T cells.
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基因ID
- 959
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UniProt
- P29965
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途径
- NF-kappaB Signaling, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
抗原
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