CTLA4 抗体 (iFluor™488)
Quick Overview for CTLA4 抗体 (iFluor™488) (ABIN7539512)
抗原
See all CTLA4 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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原理
- CD152 iFluor488 Antibody
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产品特性
- The clone A3.4H2, a mouse monoclonal antibody, selectively binds to the human 33- kDa member of the immunoglobulin superfamily, also known as Cytotoxic T-Lymphocyte Antigen 4 (CTLA-4). CD152 is a protein receptor that functions as an immune checkpoint and downregulates immune responses. It is transiently expressed on activated CD28+ T cells and binds to CD80 and CD86 present on antigen presenting cells (APC) with high avidity. Intracellular CD152 is also expressed on regulatory T cells and contributes to their inhibitory function.
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纯化方法
- Purified
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纯度
- >95 %
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免疫原
- Activated T cells
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亚型
- IgG2a, kappa
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应用备注
- FC: 5 µL/test We recommend that every lab carries out an initial titration study before running your samples to ensure that the optimal concentration is selected for your application.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, pH 7.2, 0.09 % Sodium azide and 0.2 % (w/v) BSA
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- 2-8°C, Conjugated antibodies should never be frozen.
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- CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
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别名
- CD152
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基因ID
- 929
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UniProt
- P08571
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途径
- Cancer Immune Checkpoints
抗原
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