VEGFA 抗体 (Biotin)
Quick Overview for VEGFA 抗体 (Biotin) (ABIN7539282)
抗原
See all VEGFA 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- VEGF-A antibody
-
特异性
- Chromosomal location:17C, 17 24.2cM
-
交叉反应
- 人
-
纯化方法
- Antigen-affinity purified
-
免疫原
- Recombinant mouse VEGF164 (RT #M30-001)
-
-
-
-
应用备注
- ELISA: use at 1-10 μg/mL.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.
-
缓冲液
- PBS, BSA (50x), 0.02 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.
-
有效期
- 24 months
-
-
- VEGFA (Vascular Endothelial Growth Factor A (VEGFA))
-
别名
- VEGF-A
-
背景
- Vegfa, Vpf, Vegf, Vegf120, Vegf164, Vegf188,Mouse VEGF is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis. Substantial evidence implicates VEGF in the induction of tumor metastasis and intra-ocular neovascular syndromes. VEGF signals through the three receptors, fms-like tyrosine kinase (flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product. Recombinant murine VEGF (isoform 164) is a 39.0 kDa disulfide-linked homodimeric protein consisting of two 164 amino acid polypeptide chains.
-
基因ID
- 22339
-
NCBI登录号
- NM_001025250, NP_001020421
-
UniProt
- Q00731
-
途径
- RTK signaling, Glycosaminoglycan Metabolic Process, Regulation of Cell Size, Tube Formation, Signaling Events mediated by VEGFR1 and VEGFR2, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals, VEGF Signaling
抗原
-