CCR4 抗体 (PE)
Quick Overview for CCR4 抗体 (PE) (ABIN7536961)
抗原
See all CCR4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- PE Anti-Human CD194/CCR4 Antibody [L291H4]
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纯化方法
- Purified
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亚型
- IgG1, kappa
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anti-Chemokine (C-C Motif) Receptor 4 (CCR4) (AA 201-300) antibody
CCR4 适用: 人, 大鼠 ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 4 (CCR4) antibodyCCR4 适用: 人 FACS, cELISA 宿主: 小鼠 Monoclonal KH-4F5 unconjugated
anti-Chemokine (C-C Motif) Receptor 4 (CCR4) (N-Term) antibodyCCR4 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 4 (CCR4) (Extracellular Domain) antibodyCCR4 适用: 人, 猴 ELISA, WB, FACS, IHC, IHC (p) 宿主: 山羊 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 4 (CCR4) (AA 309-360) antibodyCCR4 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 4 (CCR4) (Extracellular Domain) antibodyCCR4 适用: 人, 猴 ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 4 (CCR4) (N-Term) antibodyCCR4 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 4 (CCR4) (AA 17-39) antibodyCCR4 适用: 人 ELISA, WB, FACS, IHC (p), IHC (fro) 宿主: 山羊 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 4 (CCR4) (AA 337-351) antibodyCCR4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 4 (CCR4) (AA 180-229) antibodyCCR4 适用: 人, 小鼠, 大鼠, Cow, 犬 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
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说明
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Matching Isotype Control: (ABIN7469761)
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限制
- 仅限研究用
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缓冲液
- Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer and 1 % protein protectant.
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储存条件
- 4 °C
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储存方法
- This product can be stored at 2-8°C for 12 months. Do not freeze.
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有效期
- 12 months
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- CCR4 (Chemokine (C-C Motif) Receptor 4 (CCR4))
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别名
- CD194/CCR4
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背景
- CD194/CCR4,CKR4,K5-5,CMKBR4,ChemR13,CC-CKR-4,MGC88293,HGCN:14099,CD194, also known as CCR4, is a CC chemokine receptor. It binds CCL17 and CCL22 and is expressed on a subset of T and B cells, basophils, monocytes, and NK cells. Human Th2 cells are characterized by the expression of CCR4 and CCR8, and these receptors are regulated differently during Th2 development. Human peripheral blood Tregs can be divided into two distinct populations based on the expression of CCR4. Freshly isolated Tregs express CCR4 and presumably represent memory-type Tregs, and CCR4-?Tregs require CD3-mediated activation to acquire a regulatory activity. Depletion of CCR4+?T cells leads to Th1-type polarization of CD4+?T cells and augmentation of CD8+?T cell responses to tumor antigens. CCR4 and its ligands are important for the recruitment of memory T cells into the skin in various cutaneous immune diseases.
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UniProt
- P51679
抗原
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