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CCR4 抗体

CCR4 适用: 人 FACS, cELISA 宿主: 小鼠 Monoclonal KH-4F5 unconjugated
产品编号 ABIN179723
发货至: 中国
  • 抗原 See all CCR4 抗体
    CCR4 (Chemokine (C-C Motif) Receptor 4 (CCR4))
    适用
    • 69
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    宿主
    • 62
    • 8
    • 5
    小鼠
    克隆类型
    • 69
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    单克隆
    标记
    • 40
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    This CCR4 antibody is un-conjugated
    应用范围
    • 45
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    Flow Cytometry (FACS), Cell-ELISA (cELISA)
    特异性
    Anti-human CCR4
    纯化方法
    Protein G
    免疫原
    immunisation with human CCR4 peptide
    克隆位点
    KH-4F5
    亚型
    IgG2a
    Top Product
    Discover our top product CCR4 Primary Antibody
  • 应用备注
    Flow cytometry: 1.2 µg/10^6 cells
    Immunofluorescence: 1 µg/10^6 cells
    CELISA: 1:200 - 1:400
    For each application a titration should be performed to determine the optimal concentration.
    说明

    Synonyms: CC chemokine receptor 4

    限制
    仅限研究用
  • 浓度
    2 mg/mL
    缓冲液
    PBS, pH 7.2
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C
    储存方法
    short term: 2 °C - 8 °C, long term: -20 °C
  • 抗原
    CCR4 (Chemokine (C-C Motif) Receptor 4 (CCR4))
    别名
    CCR4 (CCR4 产品)
    别名
    CC-CKR-4 antibody, CD194 antibody, CKR4 antibody, CMKBR4 antibody, ChemR13 antibody, HGCN:14099 antibody, K5-5 antibody, Ccr4 antibody, C-C CKR-4 antibody, CHEMR1 antibody, Cmkbr4 antibody, LESTR antibody, Sdf1r antibody, C-C motif chemokine receptor 4 antibody, chemokine (C-C motif) receptor 4 antibody, CCR4 antibody, Ccr4 antibody
    背景
    CCR4 (CC chemokine receptor 4) molecule belongs to the rhodopsin family of G-protein-coupled receptors. Chemokine receptors are membrane bound molecules composed of 7-transmembrane domains and coupled to G-proteins. CCR4 binds the chemokines CCL17 (TARC) and CCL22 (MDC) and is highly expressed in most single-positive CD4(+) thymocytes especially in TH2- and regulatory T-cells. It plays a central role in T cell migration to the thymus, T cell maturation and education. CCR4 is often up-regulated in inflammation and cause conformational changes that trigger intracellular signaling pathways.
    UniProt
    P51679
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