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DLL4 抗体 (APC)

This anti-DLL4 antibody is a 小鼠 单克隆 antibody detecting DLL4 in FACS. Suitable for 人.
产品编号 ABIN7505974
发货至: 中国

Quick Overview for DLL4 抗体 (APC) (ABIN7505974)

抗原

See all DLL4 抗体
DLL4 (delta-Like 4 (DLL4))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This DLL4 antibody is conjugated to APC

应用范围

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Flow Cytometry (FACS)

克隆位点

MHD4-46
  • 原理

    Anti-DLL4 APC

    特异性

    The mouse monoclonal antibody MHD4-46 recognizes the extracellular domain of DLL4 (Delta-like ligand 4), a type I transmembrane protein which plays an important role in vascular development.

    纯化方法

    Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

    免疫原

    recombinant soluble human DLL4

    亚型

    IgG1 kappa
  • 应用备注

    Flow cytometry: Recommended dilution: 1-5 μg/mL.

    限制

    仅限研究用
  • 浓度

    0.1 mg/mL

    缓冲液

    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • 抗原

    DLL4 (delta-Like 4 (DLL4))

    别名

    DLL4

    背景

    Delta like canonical Notch ligand 4,DLL4 (Delta-like 4) is one of five ligands of Notch receptors. It interacts with Notch1 and Notch4. DLL4 is up-regulated at sites of physiologic and pathologic angiogenesis, whereas its expression is low in most adult normal tissues. It is also highly expressed in human clear-cell renal carcinomas, bladder cancers, and breast cancers. Blocking the DLL4-Notch interaction seems to be a promissing therapeutic approach.,Delta like ligand 4, AOS6, canonical Notch ligand 4

    基因ID

    54567

    UniProt

    Q9NR61

    途径

    Notch Signaling
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