FZD4 抗体 (PE)
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- 抗原 See all FZD4 抗体
- FZD4 (Frizzled Family Receptor 4 (FZD4))
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适用
- 人, Non-Human Primate
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This FZD4 antibody is conjugated to PE
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应用范围
- Flow Cytometry (FACS)
- 原理
- Anti-Hu CD344 PE
- 特异性
- The mouse monoclonal antibody CH3A4A7 recognizes an extracellular epitope of CD344 (Frizzled 4), a 7-TM protein of G-protein-coupled receptor family, which is a marker for neuronal stem cells.
- 纯化方法
- Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
- 免疫原
- WERI-RB-1 retinoblastoma cells
- 克隆位点
- CH3A4A7
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product FZD4 Primary Antibody
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- 应用备注
- Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
- 限制
- 仅限研究用
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- 缓冲液
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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- 抗原
- FZD4 (Frizzled Family Receptor 4 (FZD4))
- 别名
- CD344 (FZD4 产品)
- 背景
- Frizzled class receptor 4,CD344 (Frizzled class receptor 4) is a G-protein coupled 7-TM protein, predominantly expressed in fetal neuronal progenitor cells, neuronal intestinal cells, as well as in the kidney, lung, brain, and liver. CD344 is important for regulation of cell polarity, proliferation, and tissue development. Defects in CD344 expression, or its mutation, lead e.g. to serious failures in retinal vascularization, defects in cerebellum, progressive hearing loss, or impaired corpora lutea formation and function.,Frizzled-4, FZD4, EVR1, FEVR, GPCR
- 基因ID
- 8322
- UniProt
- Q9ULV1
- 途径
- WNT signaling, Hormone Transport, Sensory Perception of Sound
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