Integrin beta 3 抗体 (PE)
Quick Overview for Integrin beta 3 抗体 (PE) (ABIN7489343)
抗原
See all Integrin beta 3 (ITGB3) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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原理
- CD61 PE Antibody
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产品特性
- The clone C-61.13, a mouse monoclonal antibody, specifically binds to the 90-110 kDa integral cell-surface protein known as CD61 or Integrin beta-3 (β3) that in humans is encoded by the ITGB3 gene. CD61 is expressed on the surface of platelets and megakaryocytes. CD61 (platelet glycoproteins IIIa) and CD41 (platelet glycoprotein IIb) form a calcium-dependent heterodimeric complex. This glycoprotein complex (GPIIb-IIIa) binds plasma proteins, such as fibrinogen, fibronectin, von Willebrand factor, and vitronectin, and plays a critical role in platelet aggregation.
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纯化方法
- Purified
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纯度
- >95 %
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免疫原
- Recombinant human ITGB3 protein
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亚型
- IgG1, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- 2-8°C, Conjugated antibodies should never be frozen.
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- Integrin beta 3 (ITGB3)
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别名
- CD61
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基因ID
- 933
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NCBI登录号
- NM_001771
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UniProt
- P20273
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途径
- Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex
抗原
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