Recombinant Tyrosinase-Related Protein 1 抗体
Quick Overview for Recombinant Tyrosinase-Related Protein 1 抗体 (ABIN7487762)
抗原
See all Tyrosinase-Related Protein 1 (TYRP1) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-TRP-1, gp75 [TA99], Human IgG1, kappa
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特异性
- Binds Tyrosinase-related protein-1 (TRP-1), a 70-75k enzyme located in melanocytes, which are specialized cells that produce a pigment called melanin, helping to stabilize tyrosinase, which is the enzyme responsible for the first step in melanin production and determine the shape of melanosomes, which are the structures in melanocytes where melanin is produced.
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产品特性
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Original Species of Ab: Mouse
Original Format of Ab: IgG2a
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纯化方法
- Protein A affinity purified
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免疫原
- 70-75 kDa pigmentation-associated glycoprotein in human melanoma cell lines.
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亚型
- IgG1 kappa
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应用备注
- This antibody binds to human and murine TRP-1 and had been under evaluation for the treatment of tumours.
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说明
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This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- Tyrosinase-Related Protein 1 (TYRP1)
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别名
- TRP-1, gp75
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背景
- Melanoma antigen gp75, 5,6-dihydroxyindole-2-carboxylic acid oxidase, DHICA oxidase, Catalase B, Glycoprotein 75, Tyrosinase-related protein 1, TRP, TRP-1, TRP1
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UniProt
- P17643
抗原
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