Recombinant CEA 抗体
Quick Overview for Recombinant CEA 抗体 (ABIN7487714)
抗原
See all CEA 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-CEA [BW431/26], Rabbit IgG, kappa
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特异性
- This antibody recognizes and binds human carcinoembryonic antigen in its purified state as well as on tissue sections.
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产品特性
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Original Species of Ab: Mouse
Original Format of Ab: IgG3
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纯化方法
- Protein A affinity purified
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免疫原
- The original antibody was generated by immunizing mice with CEA positive adenocarcinoma cells preferably from lungs.
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亚型
- IgG kappa
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anti-Carcinoembryonic Antigen Gene Family (CEA) (AA 448-572) antibody
CEA 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Carcinoembryonic Antigen Gene Family (CEA) antibodyCEA 适用: 人 WB, ELISA, IHC (p), IF (p) 宿主: 小鼠 Monoclonal B5 unconjugated
anti-Carcinoembryonic Antigen Gene Family (CEA) (AA 315-365) antibodyCEA 适用: 人 WB, ELISA, IHC (p), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Carcinoembryonic Antigen Gene Family (CEA) antibodyCEA 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal 1C7 unconjugated
anti-Carcinoembryonic Antigen Gene Family (CEA) antibodyCEA 适用: 人 ELISA, ICC 宿主: 小鼠 Monoclonal 3G12 unconjugated
anti-Carcinoembryonic Antigen Gene Family (CEA) (AA 400-429) antibodyCEA 适用: 人 WB, IHC, FACS, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Carcinoembryonic Antigen Gene Family (CEA) antibodyCEA 适用: 人 ELISA, IHC (p), IF (p), IF (cc) 宿主: 小鼠 Monoclonal C3 unconjugated
anti-Carcinoembryonic Antigen Gene Family (CEA) antibodyCEA 适用: 人 IHC 宿主: 兔 Monoclonal MSVA-465R unconjugated Recombinant Antibody
anti-Carcinoembryonic Antigen Gene Family (CEA) (AA 566-698) antibodyCEA 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Carcinoembryonic Antigen Gene Family (CEA) (AA 544-771) antibodyCEA 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Technetium 99-labeled (Tc-99m) BW431/26 has been used in the diagnosis and detection of colorectal carcinomas, breast cancers, bladder carcinomas, lung adenocarcinomas and their recurrences by immunoscintigraphy (PMID: 2602902, 2662074, 2685692, 2297747, 2157833, 2166552, 2383485, 1984945 ). The use of Tc-99m-BW 431/26 immunoconjugates in immunoscintigraphy resulted in reduction of radiation dose for the patient down to 5 % of the dose applied as compared with I-131 labelled MAbs (PMID: 3262953). Humanized version of this antibody also shows similar binding affinity as compared to its murine parent antibody (PMID: 1762576).
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说明
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This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG3 format, for improved compatibility with existing reagents, assays and techniques.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- CEA (Carcinoembryonic Antigen Gene Family (CEA))
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别名
- CEA
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背景
- Carcinoembryonic antigen, Carcinoembryonic antigen-related cell adhesion molecule 5, CEACAM5, Meconium antigen 100, CD66e
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UniProt
- P06731
抗原
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