电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

Recombinant CEA 抗体

The 小鼠 单克隆 anti-CEA antibody (Clone BW431-26) (ABIN7487713) specifically detects CEA in ISG. The antibody is reactive with 人 samples.
产品编号 ABIN7487713
发货至: 中国
Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant CEA 抗体 (ABIN7487713)

抗原

See all CEA 抗体
CEA (Carcinoembryonic Antigen Gene Family (CEA))

抗体类型

Recombinant Antibody

适用

  • 171
  • 11
  • 4
  • 3
  • 1

宿主

  • 105
  • 75
  • 3
  • 1
  • 1
  • 1
小鼠

克隆类型

  • 136
  • 45
  • 4
单克隆

标记

  • 70
  • 18
  • 9
  • 6
  • 5
  • 5
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CEA antibody is un-conjugated

应用范围

  • 84
  • 65
  • 43
  • 31
  • 29
  • 27
  • 27
  • 24
  • 22
  • 16
  • 13
  • 10
  • 5
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Immunoscintigraphy (ISG)

克隆位点

BW431-26
  • 原理

    Anti-CEA [BW431/26], Mouse IgG3, kappa

    特异性

    This antibody recognizes and binds human carcinoembryonic antigen in its purified state as well as on tissue sections.

    产品特性

    Original Species of Ab: Mouse

    Original Format of Ab: IgG3

    纯化方法

    Protein A affinity purified

    免疫原

    The original antibody was generated by immunizing mice with CEA positive adenocarcinoma cells preferably from lungs.

    亚型

    IgG3 kappa
  • 应用备注

    Technetium 99-labeled (Tc-99m) BW431/26 has been used in the diagnosis and detection of colorectal carcinomas, breast cancers, bladder carcinomas, lung adenocarcinomas and their recurrences by immunoscintigraphy (PMID: 2602902, 2662074, 2685692, 2297747, 2157833, 2166552, 2383485, 1984945 ). The use of Tc-99m-BW 431/26 immunoconjugates in immunoscintigraphy resulted in reduction of radiation dose for the patient down to 5 % of the dose applied as compared with I-131 labelled MAbs (PMID: 3262953). Humanized version of this antibody also shows similar binding affinity as compared to its murine parent antibody (PMID: 1762576).

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • 抗原

    CEA (Carcinoembryonic Antigen Gene Family (CEA))

    别名

    CEA

    背景

    Carcinoembryonic antigen, Carcinoembryonic antigen-related cell adhesion molecule 5, CEACAM5, Meconium antigen 100, CD66e

    UniProt

    P06731
You are here: