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Recombinant CEA 抗体

This anti-CEA antibody is a 小鼠 单克隆 antibody detecting CEA in ISG. Suitable for 人.
产品编号 ABIN7487713
发货至: 中国

Quick Overview for Recombinant CEA 抗体 (ABIN7487713)

抗原

See all CEA 抗体
CEA (Carcinoembryonic Antigen Gene Family (CEA))

抗体类型

Recombinant Antibody

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CEA antibody is un-conjugated

应用范围

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Immunoscintigraphy (ISG)

克隆位点

BW431-26
  • 原理

    Anti-CEA [BW431/26], Mouse IgG3, kappa

    特异性

    This antibody recognizes and binds human carcinoembryonic antigen in its purified state as well as on tissue sections.

    产品特性

    Original Species of Ab: Mouse

    Original Format of Ab: IgG3

    纯化方法

    Protein A affinity purified

    免疫原

    The original antibody was generated by immunizing mice with CEA positive adenocarcinoma cells preferably from lungs.

    亚型

    IgG3 kappa
  • 应用备注

    Technetium 99-labeled (Tc-99m) BW431/26 has been used in the diagnosis and detection of colorectal carcinomas, breast cancers, bladder carcinomas, lung adenocarcinomas and their recurrences by immunoscintigraphy (PMID: 2602902, 2662074, 2685692, 2297747, 2157833, 2166552, 2383485, 1984945 ). The use of Tc-99m-BW 431/26 immunoconjugates in immunoscintigraphy resulted in reduction of radiation dose for the patient down to 5 % of the dose applied as compared with I-131 labelled MAbs (PMID: 3262953). Humanized version of this antibody also shows similar binding affinity as compared to its murine parent antibody (PMID: 1762576).

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • 抗原

    CEA (Carcinoembryonic Antigen Gene Family (CEA))

    别名

    CEA

    背景

    Carcinoembryonic antigen, Carcinoembryonic antigen-related cell adhesion molecule 5, CEACAM5, Meconium antigen 100, CD66e

    UniProt

    P06731
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