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PRKDC 抗体 (C-Term)

This anti-PRKDC antibody is a 兔 多克隆 antibody detecting PRKDC in WB, IF, IHC (p) 和 ICC. Suitable for 人.
产品编号 ABIN7469547
发货至: 中国

Quick Overview for PRKDC 抗体 (C-Term) (ABIN7469547)

抗原

See all PRKDC 抗体
PRKDC (Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC))

适用

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宿主

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克隆类型

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多克隆

标记

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This PRKDC antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
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    C-Term

    交叉反应

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human DNA-PKcs. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: 293T , Molt-4 , NCI-H929

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    PRKDC (Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC))

    别名

    DNA-PKcs

    背景

    Synonyms: protein kinase, DNA-activated, catalytic subunit , DNA-PKC , DNA-PKcs , DNAPK , DNAPKc , DNPK1 , HYRC , HYRC1 , IMD26 , XRCC7 , p350

    Background: The PRKDC gene encodes the catalytic subunit of a nuclear DNA-dependent serine/threonine protein kinase (DNA-PK). The second component is the autoimmune antigen Ku (MIM 152690), which is encoded by the G22P1 gene on chromosome 22q. On its own, the catalytic subunit of DNA-PK is inactive and relies on the G22P1 component to direct it to the DNA and trigger its kinase activity, PRKDC must be bound to DNA to express its catalytic properties.[supplied by OMIM]

    分子量

    469 kDa

    基因ID

    5591

    UniProt

    P78527

    途径

    DNA Damage Repair, Production of Molecular Mediator of Immune Response
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