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FANCD2 抗体

This anti-FANCD2 antibody is a 小鼠 单克隆 antibody detecting FANCD2 in WB, ELISA, IF 和 ICC. Suitable for 人.
产品编号 ABIN7469359
发货至: 中国

Quick Overview for FANCD2 抗体 (ABIN7469359)

抗原

See all FANCD2 抗体
FANCD2 (Fanconi Anemia, Complementation Group D2 (FANCD2))

适用

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宿主

  • 71
小鼠

克隆类型

  • 61
  • 10
单克隆

标记

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This FANCD2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

质量等级

KO Validated

克隆位点

103
  • 交叉反应

    纯化方法

    Protein G purified

    免疫原

    Human FANCD2 fusion protein

    亚型

    IgG1
  • 应用备注

    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: 293T , HeLa Validation: KO/KD

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, No Preservative

    储存液

    Without preservative

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    FANCD2 (Fanconi Anemia, Complementation Group D2 (FANCD2))

    别名

    FANCD2

    背景

    Synonyms: FA complementation group D2 , FA-D2 , FA4 , FACD , FAD , FAD2 , FANCD

    Background: The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity, they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group D2. This protein is monoubiquinated in response to DNA damage, resulting in its localization to nuclear foci with other proteins (BRCA1 AND BRCA2) involved in homology-directed DNA repair. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]

    分子量

    164 kDa

    基因ID

    2177

    UniProt

    Q9BXW9

    途径

    DNA Damage Repair
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