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APC 抗体 (C-Term)

This anti-APC antibody is a 兔 多克隆 antibody detecting APC in WB, IHC, IF, ICC 和 IHC (p). Suitable for 人.
产品编号 ABIN7469239
发货至: 中国

Quick Overview for APC 抗体 (C-Term) (ABIN7469239)

抗原

See all APC 抗体
APC (Adenomatous Polyposis Coli (APC))

适用

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宿主

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克隆类型

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多克隆

标记

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This APC antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    C-Term

    交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human APC. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.44 mg/mL

    缓冲液

    1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    APC (Adenomatous Polyposis Coli (APC))

    别名

    APC

    背景

    Synonyms: APC regulator of WNT signaling pathway , BTPS2 , DP2 , DP2.5 , DP3 , GS , PPP1R46

    Background: This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product. [provided by RefSeq]

    分子量

    312 kDa

    基因ID

    324

    UniProt

    P25054

    途径

    WNT signaling, Stem Cell Maintenance, Cell-Cell Junction Organization
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