ASCL1 抗体
Quick Overview for ASCL1 抗体 (ABIN7469231)
抗原
See all ASCL1 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 犬, 人, 大鼠
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human ASCL1. The exact sequence is proprietary.
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亚型
- IgG
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应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: U87-MG , SK-N-SH , IMR32 , SK-N-AS , PC-12 , Rat2 , SH-SY5Y nuclear extract Validation: Orthogonal
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- ASCL1 (Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1))
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别名
- ASCL1
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背景
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Synonyms: achaete-scute family bHLH transcription factor 1 , ASH1 , HASH1 , MASH1 , bHLHa46
Background: This gene encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases. [provided by RefSeq]
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分子量
- 25 kDa
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基因ID
- 429
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UniProt
- P50553
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途径
- Dopaminergic Neurogenesis
抗原
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