PKLR 抗体
Quick Overview for PKLR 抗体 (ABIN7468839)
抗原
See all PKLR 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody is raised against the R-Type isoform. Based on a BLAST result, it may also react with the L-Type isoform.
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human Pyruvate Kinase (liver/RBC). The exact sequence is proprietary.
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亚型
- IgG
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anti-Pyruvate Kinase, Liver and RBC (PKLR) (AA 219-420) antibody
PKLR 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Kinase, Liver and RBC (PKLR) (AA 114-323) antibodyPKLR 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Kinase, Liver and RBC (PKLR) (AA 1-574) antibodyPKLR 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Kinase, Liver and RBC (PKLR) (AA 1-574) antibodyPKLR 适用: 人 WB, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Pyruvate Kinase, Liver and RBC (PKLR) (Internal Region) antibodyPKLR 适用: 人, 小鼠, 大鼠 WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Kinase, Liver and RBC (PKLR) (N-Term) antibodyPKLR 适用: 人, 小鼠, 大鼠, 犬, C. elegans WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Kinase, Liver and RBC (PKLR) (N-Term) antibodyPKLR 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔, 马, Pig, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Kinase, Liver and RBC (PKLR) (AA 56-105) antibodyPKLR 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔, Bat, 猴, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Kinase, Liver and RBC (PKLR) (AA 521-551), (C-Term) antibodyPKLR 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB3694 unconjugated
anti-Pyruvate Kinase, Liver and RBC (PKLR) (AA 1-30), (N-Term) antibodyPKLR 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB03692 unconjugated
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应用备注
- WB: 1:500-1:10000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: K562 , Raw264.7 , rat liver , human PKLR-transfected 293T cells Validation: Overexpression
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.62 mg/mL
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缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- PKLR (Pyruvate Kinase, Liver and RBC (PKLR))
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别名
- pyruvate kinase L/R
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背景
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Synonyms: pyruvate kinase L/R , PK1 , PKL , PKRL , RPK
Background: The protein encoded by this gene is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
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分子量
- 62 kDa
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基因ID
- 5313
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UniProt
- P30613
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途径
- Ribonucleoside Biosynthetic Process
抗原
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