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PAK3 抗体

This anti-PAK3 antibody is a 兔 多克隆 antibody detecting PAK3 in WB. Suitable for 人.
产品编号 ABIN7468705
发货至: 中国

Quick Overview for PAK3 抗体 (ABIN7468705)

抗原

See all PAK3 抗体
PAK3

适用

  • 78
  • 32
  • 21
  • 3

宿主

  • 72
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  • 2

克隆类型

  • 71
  • 9
多克隆

标记

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This PAK3 antibody is un-conjugated

应用范围

  • 60
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Western Blotting (WB)
  • 交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human PAK3. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: NIH-3T3 , BCL-1 , IMR32 , mouse brain , rat brain

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.74 mg/mL

    缓冲液

    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    PAK3

    别名

    p21 (RAC1) activated kinase 3

    背景

    Synonyms: p21 (RAC1) activated kinase 3 , ARA , MRX30 , MRX47 , OPHN3 , PAK-3 , PAK3beta , bPAK , beta-PAK

    Background: PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine/threonine p21-activating kinases, serve as targets for the small GTP binding proteins Cdc42 and RAC and have been implicated in a wide range of biological activities. The protein encoded by this gene forms an activated complex with GTP-bound RAS-like (P21), CDC2 and RAC1 proteins which then catalyzes a variety of targets. This protein may be necessary for dendritic development and for the rapid cytoskeletal reorganization in dendritic spines associated with synaptic plasticity. Defects in this gene are the cause of non-syndromic mental retardation X-linked type 30 (MRX30), also called X-linked mental retardation type 47 (MRX47). Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]

    分子量

    62 kDa

    基因ID

    5063

    UniProt

    O75914
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