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PAK4 抗体

This anti-PAK4 antibody is a 兔 多克隆 antibody detecting PAK4 in WB. Suitable for 人.
产品编号 ABIN7468702
发货至: 中国

Quick Overview for PAK4 抗体 (ABIN7468702)

抗原

See all PAK4 抗体
PAK4 (P21-Activated Kinase 4 (PAK4))

适用

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宿主

  • 68
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克隆类型

  • 67
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多克隆

标记

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This PAK4 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 交叉反应

    人, 小鼠

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human PAK4. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Validation: Orthogonal

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    PAK4 (P21-Activated Kinase 4 (PAK4))

    别名

    p21 (RAC1) activated kinase 4

    背景

    Synonyms: p21 (RAC1) activated kinase 4

    Background: PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. They serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq]

    分子量

    64 kDa

    基因ID

    10298

    UniProt

    O96013

    途径

    RTK signaling
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