IFT57 抗体
Quick Overview for IFT57 抗体 (ABIN7468496)
抗原
See all IFT57 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human HIPPI. The exact sequence is proprietary.
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亚型
- IgG
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anti-Intraflagellar Transport 57 Homolog (IFT57) (AA 170-429) antibody
IFT57 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Intraflagellar Transport 57 Homolog (IFT57) (AA 1-429) antibodyIFT57 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Intraflagellar Transport 57 Homolog (IFT57) (AA 214-312) antibodyIFT57 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1G8 unconjugated
anti-Intraflagellar Transport 57 Homolog (IFT57) (Internal Region) antibodyIFT57 适用: 人, 小鼠, 大鼠, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Intraflagellar Transport 57 Homolog (IFT57) (AA 159-193) antibodyIFT57 适用: 人 WB 宿主: 兔 Polyclonal RB57869 unconjugated
anti-Intraflagellar Transport 57 Homolog (IFT57) (AA 214-312) antibodyIFT57 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Intraflagellar Transport 57 Homolog (IFT57) (Internal Region) antibodyVerified IFT57 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: Raji
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.9 mg/mL
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缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- IFT57 (Intraflagellar Transport 57 Homolog (IFT57))
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别名
- intraflagellar transport 57
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背景
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Synonyms: intraflagellar transport 57 , ESRRBL1 , HIPPI , MHS4R2 , OFD18
Background: Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity). Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator, however the relevance of such function remains unclear.
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分子量
- 49 kDa
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基因ID
- 55081
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UniProt
- Q9NWB7
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途径
- Hedgehog Signaling, Positive Regulation of Endopeptidase Activity
抗原
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