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IFT57 抗体

IFT57 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7468495
发货至: 中国
  • 抗原 See all IFT57 抗体
    IFT57 (Intraflagellar Transport 57 Homolog (IFT57))
    适用
    • 35
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    宿主
    • 30
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    克隆类型
    • 32
    • 3
    多克隆
    标记
    • 15
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    This IFT57 antibody is un-conjugated
    应用范围
    • 29
    • 13
    • 13
    • 11
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the center region of human HIPPI. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product IFT57 Primary Antibody
  • 应用备注
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: H1299

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.52 mg/mL
    缓冲液
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    IFT57 (Intraflagellar Transport 57 Homolog (IFT57))
    别名
    intraflagellar transport 57 (IFT57 产品)
    背景

    Synonyms: intraflagellar transport 57 , ESRRBL1 , HIPPI , MHS4R2 , OFD18

    Background: Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity). Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator, however the relevance of such function remains unclear.

    分子量
    49 kDa
    基因ID
    55081
    UniProt
    Q9NWB7
    途径
    Hedgehog Signaling, Positive Regulation of Endopeptidase Activity
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