DPF3 抗体
Quick Overview for DPF3 抗体 (ABIN7468201)
抗原
See all DPF3 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human CERD4. The exact sequence is proprietary.
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亚型
- IgG
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anti-D4, Zinc and Double PHD Fingers, Family 3 (DPF3) (Middle Region) antibody
DPF3 适用: 人, 小鼠, 大鼠, 豚鼠, 马, 兔, Cow, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-D4, Zinc and Double PHD Fingers, Family 3 (DPF3) (N-Term) antibodyDPF3 适用: 人, 小鼠, 大鼠, 豚鼠, 马, 兔, Cow, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-D4, Zinc and Double PHD Fingers, Family 3 (DPF3) (AA 1-100) antibodyDPF3 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-D4, Zinc and Double PHD Fingers, Family 3 (DPF3) (N-Term) antibodyDPF3 适用: 人, 小鼠, 豚鼠, 马, 兔, 猴, Pig, 斑马鱼, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-D4, Zinc and Double PHD Fingers, Family 3 (DPF3) (AA 108-157) antibodyDPF3 适用: 人, 小鼠, 大鼠, 豚鼠, 马, 兔, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-D4, Zinc and Double PHD Fingers, Family 3 (DPF3) (AA 71-120) antibodyDPF3 适用: 人, 小鼠, 大鼠, 豚鼠, 马, 兔, Cow, 犬, 猴, Pig, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-D4, Zinc and Double PHD Fingers, Family 3 (DPF3) (AA 1-196) antibodyDPF3 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-D4, Zinc and Double PHD Fingers, Family 3 (DPF3) (AA 90-200) antibodyDPF3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-D4, Zinc and Double PHD Fingers, Family 3 (DPF3) (N-Term) antibodyDPF3 适用: 人, 小鼠, 大鼠, 豚鼠, 马, 兔, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: IMR32
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- DPF3 (D4, Zinc and Double PHD Fingers, Family 3 (DPF3))
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别名
- double PHD fingers 3
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背景
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Synonyms: double PHD fingers 3 , BAF45C , CERD4
Background: Belongs to the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity). Muscle-specific component of the BAF complex, a multiprotein complex involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Specifically binds acetylated lysines on histone 3 and 4 (H3K14ac, H3K9ac, H4K5ac, H4K8ac, H4K12ac, H4K16ac). In the complex, it acts as a tissue-specific anchor between histone acetylations and methylations and chromatin remodeling. It thereby probably plays an essential role in heart and skeletal muscle development.
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分子量
- 43 kDa
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基因ID
- 8110
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UniProt
- Q92784
抗原
-
