BRCA2 抗体 (AA 2336-2478)
Quick Overview for BRCA2 抗体 (AA 2336-2478) (ABIN7468065)
抗原
See all BRCA2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 2336-2478
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交叉反应
- 人
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纯化方法
- Protein G purified
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免疫原
- Amino acids 2336-2478 of human BRCA2 expressed in E. coli. BRCA2-P400.
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亚型
- IgG1
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anti-Breast Cancer 2, Early Onset (BRCA2) (AA 21-130) antibody
BRCA2 适用: 人 WB, ELISA, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Breast Cancer 2, Early Onset (BRCA2) antibodyBRCA2 适用: 人, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Breast Cancer 2, Early Onset (BRCA2) (AA 2990-3232) antibodyBRCA2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Breast Cancer 2, Early Onset (BRCA2) (AA 3319-3418) antibodyBRCA2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3D12 unconjugated
anti-Breast Cancer 2, Early Onset (BRCA2) (AA 1-300) antibodyBRCA2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Breast Cancer 2, Early Onset (BRCA2) (AA 2913-3151) antibodyBRCA2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Breast Cancer 2, Early Onset (BRCA2) (AA 2308-2537) antibodyBRCA2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Breast Cancer 2, Early Onset (BRCA2) (AA 2737-2874) antibodyBRCA2 适用: 斑马鱼 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Breast Cancer 2, Early Onset (BRCA2) (pSer3291) antibodyBRCA2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Breast Cancer 2, Early Onset (BRCA2) (AA 251-495) antibodyBRCA2 适用: 人 WB 宿主: 小鼠 Monoclonal 1643CT739-91-87 unconjugated
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应用备注
- Do not boil samples for longer than two minutes. For WB: Use at a concentration of 1-5 μg/mL. Predicted molecular weight: 380 kDa. Optimal dilutions/concentrations should be determined by the reseracher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, No Preservative
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储存液
- Without preservative
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- BRCA2 (Breast Cancer 2, Early Onset (BRCA2))
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别名
- BRCA2 DNA repair associated
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背景
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Synonyms: BRCA2 DNA repair associated , BRCC2 , BROVCA2 , FACD , FAD , FAD1 , FANCD , FANCD1 , GLM3 , PNCA2 , XRCC11
Background: Inherited mutations in BRCA1 and this gene, BRCA2, confer increased lifetime risk of developing breast or ovarian cancer. Both BRCA1 and BRCA2 are involved in maintenance of genome stability, specifically the homologous recombination pathway for double-strand DNA repair. The BRCA2 protein contains several copies of a 70 aa motif called the BRC motif, and these motifs mediate binding to the RAD51 recombinase which functions in DNA repair. BRCA2 is considered a tumor suppressor gene, as tumors with BRCA2 mutations generally exhibit loss of heterozygosity (LOH) of the wild-type allele. [provided by RefSeq, Dec 2008]
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分子量
- 384 kDa
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基因ID
- 675
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UniProt
- P51587
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途径
- DNA Damage Repair, M Phase, Maintenance of Protein Location
抗原
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