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TGFB3 抗体

The 兔 多克隆 anti-TGFB3 antibody is suitable to detect TGFB3 in samples from 人. It has been validated for WB 和 IHC (p).
产品编号 ABIN7467865
发货至: 中国
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北京 101111
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for TGFB3 抗体 (ABIN7467865)

抗原

See all TGFB3 抗体
TGFB3 (Transforming Growth Factor, beta 3 (TGFB3))

适用

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宿主

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克隆类型

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多克隆

标记

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This TGFB3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 交叉反应

    人, 小鼠

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human TGF beta 3. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:5000-1:20000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.43 mg/mL

    缓冲液

    1XPBS pH 7, 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    TGFB3 (Transforming Growth Factor, beta 3 (TGFB3))

    别名

    transforming growth factor beta 3

    背景

    Transforming growth factor beta 3 , ARVD , ARVD1 , LDS5 , RNHF , TGF-beta3,This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. This protein is involved in embryogenesis and cell differentiation, and may play a role in wound healing. Mutations in this gene are a cause of aortic aneurysms and dissections, as well as familial arrhythmogenic right ventricular dysplasia 1. [provided by RefSeq, Aug 2016]

    分子量

    47 kDa

    基因ID

    7043

    UniProt

    P10600

    途径

    Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus
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