CCR2 抗体 (N-Term)
Quick Overview for CCR2 抗体 (N-Term) (ABIN7467199)
抗原
See all CCR2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
 - N-Term
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交叉反应
 - 人
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纯化方法
 - Purified by antigen-affinity chromatography.
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免疫原
 - Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human CCR2. The exact sequence is proprietary.
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亚型
 - IgG
 
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应用备注
 - WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Validation: Orthogonal, Overexpression
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限制
 - 仅限研究用
 
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状态
 - Liquid
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浓度
 - 1.95 mg/mL
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缓冲液
 - 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
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储存液
 - ProClin
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注意事项
 - This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
 - 4 °C,-20 °C
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储存方法
 - Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
 
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- CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))
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别名
 - C-C motif chemokine receptor 2
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背景
 - C-C motif chemokine receptor 2 , CC-CKR-2 , CCR-2 , CCR2A , CCR2B , CD192 , CKR2 , CKR2A , CKR2B , CMKBR2 , MCP-1-R,The protein encoded by this gene is a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The encoded protein mediates agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This protein can also be a coreceptor with CD4 for HIV-1 infection. This gene is located in the chemokine receptor gene cluster region of chromosome 3. [provided by RefSeq, Aug 2017]
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分子量
 - 42 kDa
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基因ID
 - 729230
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UniProt
 - P41597
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途径
 - cAMP Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
 
抗原
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