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IGF2R 抗体 (AA 2201-2400)

Cited in 2+ publications. This 兔 多克隆 anti-IGF2R antibody specifically detects IGF2R in ELISA, FACS, IHC (p), IF (cc), IF (p) 和 IHC (fro). The antibody is reactive with 人 samples.
产品编号 ABIN719711
发货至: 中国
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中国
北京 101111
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for IGF2R 抗体 (AA 2201-2400) (ABIN719711)

抗原

See all IGF2R 抗体
IGF2R (Insulin-Like Growth Factor 2 Receptor (IGF2R))

适用

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宿主

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克隆类型

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多克隆

标记

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This IGF2R antibody is un-conjugated

应用范围

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ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

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    AA 2201-2400

    交叉反应

    预测反应

    Mouse,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human IGF2R/Mannose 6 Phosphate Receptor

    亚型

    IgG
  • 应用备注

    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • Geng, Yang, Li, Song, Liu, Qiu, Liu, Yang: "Insulin-like growth factor-2 enhances functions of antigen (Ag)-specific regulatory B cells." in: The Journal of biological chemistry, Vol. 289, Issue 25, pp. 17941-50, (2014) (PubMed).

    Yang, Liu, Li, Wen, Zhu, Xu: "Insulin-Like Growth Factor-1 Modulates Polycomb Cbx8 Expression and Inhibits Colon Cancer Cell Apoptosis." in: Cell biochemistry and biophysics, (2014) (PubMed).

  • 抗原

    IGF2R (Insulin-Like Growth Factor 2 Receptor (IGF2R))

    别名

    IGF2R

    背景

    Synonyms: Cation-independent mannose-6-phosphate receptor, CI Man-6-P receptor, CI-MPR, M6PR, 300 kDa mannose 6-phosphate receptor, MPR 300, Insulin-like growth factor 2 receptor, Insulin-like growth factor II receptor, IGF-II receptor, M6P/IGF2 receptor, M6P/IGF2R, CD222, IGF2R, MPRI

    Background: Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2. Acts as a positive regulator of T-cell coactivation, by binding DPP4.

    基因ID

    3482

    UniProt

    P11717
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