IGF2R 抗体 (AA 2201-2400)
Quick Overview for IGF2R 抗体 (AA 2201-2400) (ABIN719711)
抗原
See all IGF2R 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 2201-2400
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交叉反应
- 人
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预测反应
- Mouse,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human IGF2R/Mannose 6 Phosphate Receptor
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亚型
- IgG
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应用备注
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ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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: "Insulin-like growth factor-2 enhances functions of antigen (Ag)-specific regulatory B cells." in: The Journal of biological chemistry, Vol. 289, Issue 25, pp. 17941-50, (2014) (PubMed).
: "Insulin-Like Growth Factor-1 Modulates Polycomb Cbx8 Expression and Inhibits Colon Cancer Cell Apoptosis." in: Cell biochemistry and biophysics, (2014) (PubMed).
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: "Insulin-like growth factor-2 enhances functions of antigen (Ag)-specific regulatory B cells." in: The Journal of biological chemistry, Vol. 289, Issue 25, pp. 17941-50, (2014) (PubMed).
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- IGF2R (Insulin-Like Growth Factor 2 Receptor (IGF2R))
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别名
- IGF2R
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背景
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Synonyms: Cation-independent mannose-6-phosphate receptor, CI Man-6-P receptor, CI-MPR, M6PR, 300 kDa mannose 6-phosphate receptor, MPR 300, Insulin-like growth factor 2 receptor, Insulin-like growth factor II receptor, IGF-II receptor, M6P/IGF2 receptor, M6P/IGF2R, CD222, IGF2R, MPRI
Background: Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2. Acts as a positive regulator of T-cell coactivation, by binding DPP4.
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基因ID
- 3482
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UniProt
- P11717
抗原
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