SF3B3 抗体 (N-Term)
Quick Overview for SF3B3 抗体 (N-Term) (ABIN7466347)
抗原
See all SF3B3 抗体适用
宿主
克隆类型
标记
应用范围
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                                            抗原表位
- N-Term
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                                            交叉反应
- 人, 小鼠
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                                            纯化方法
- Purified by antigen-affinity chromatography.
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                                            免疫原
- Recombinant protein encompassing a sequence within the N-terminus region of human SAP130. The exact sequence is proprietary.
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                                            亚型
- IgG
 
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                                            应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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                                            说明
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                        Positive Control: IMR32 
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                                            限制
- 仅限研究用
 
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                                            状态
- Liquid
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                                            浓度
- 1 mg/mL
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                                            缓冲液
- 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal
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                                            储存液
- Thimerosal (Merthiolate)
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                                            注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            储存条件
- 4 °C,-20 °C
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                                            储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
 
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    - SF3B3 (Splicing Factor 3b, Subunit 3, 130kDa (SF3B3))
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                                            别名
- splicing factor 3b subunit 3
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                                            背景
- Splicing factor 3b subunit 3 , RSE1 , SAP130 , SF3b130 , STAF130,This gene encodes subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 3 has also been identified as a component of the STAGA (SPT3-TAF(II)31-GCN5L acetylase) transcription coactivator-HAT (histone acetyltransferase) complex, and the TFTC (TATA-binding-protein-free TAF(II)-containing complex). These complexes may function in chromatin modification, transcription, splicing, and DNA repair. [provided by RefSeq]
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                                            分子量
- 136 kDa
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                                            基因ID
- 23450
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                                            UniProt
- Q15393
 抗原
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