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LRP1 抗体 (C-Term)

This anti-LRP1 antibody is a 兔 多克隆 antibody detecting LRP1 in WB. Suitable for 人.
产品编号 ABIN7465918
发货至: 中国

Quick Overview for LRP1 抗体 (C-Term) (ABIN7465918)

抗原

See all LRP1 抗体
LRP1 (Low Density Lipoprotein Receptor-Related Protein 1 (LRP1))

适用

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宿主

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克隆类型

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多克隆

标记

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This LRP1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
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    C-Term

    交叉反应

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the C-terminus region of human LRP1 (85kDa subunit). The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: HeLa

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    LRP1 (Low Density Lipoprotein Receptor-Related Protein 1 (LRP1))

    别名

    LDL receptor related protein 1

    背景

    LDL receptor related protein 1 , A2MR , APOER , APR , CD91 , IGFBP-3R , IGFBP3R , IGFBP3R1 , KPA , LRP , LRP1A , TGFBR5,This gene encodes a member of the low-density lipoprotein receptor family of proteins. The encoded preproprotein is proteolytically processed by furin to generate 515 kDa and 85 kDa subunits that form the mature receptor (PMID: 8546712). This receptor is involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells. In addition, the encoded protein is necessary for the alpha 2-macroglobulin-mediated clearance of secreted amyloid precursor protein and beta-amyloid, the main component of amyloid plaques found in Alzheimer patients. Expression of this gene decreases with age and has been found to be lower than controls in brain tissue from Alzheimer's disease patients. [provided by RefSeq, Oct 2015]

    分子量

    505 kDa

    基因ID

    4035

    UniProt

    Q07954

    途径

    Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling
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