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H2AFX 抗体 (N-Term)

This anti-H2AFX antibody is a 兔 多克隆 antibody detecting H2AFX in WB, IF, IHC (p) 和 ICC. Suitable for 人.
产品编号 ABIN7465740
发货至: 中国

Quick Overview for H2AFX 抗体 (N-Term) (ABIN7465740)

抗原

See all H2AFX 抗体
H2AFX (H2A Histone Family, Member X (H2AFX))

适用

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宿主

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克隆类型

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多克隆

标记

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This H2AFX antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
  • 抗原表位

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    N-Term

    交叉反应

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human Histone H2A.X. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: HCT116

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.66 mg/mL

    缓冲液

    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    H2AFX (H2A Histone Family, Member X (H2AFX))

    别名

    H2A histone family member X

    背景

    H2A histone family member X , H2A.X , H2A/X , H2AX,Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [provided by RefSeq]

    分子量

    15 kDa

    基因ID

    3014

    UniProt

    P16104

    途径

    Telomere Maintenance, DNA Damage Repair, Positive Regulation of Response to DNA Damage Stimulus
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