Patched 1 抗体 (C-Term)
Quick Overview for Patched 1 抗体 (C-Term) (ABIN7465681)
抗原
See all Patched 1 (PTCH1) 抗体适用
宿主
克隆类型
标记
应用范围
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                                            抗原表位
- C-Term
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                                            交叉反应
- 人
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                                            纯化方法
- Purified by antigen-affinity chromatography.
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                                            免疫原
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human PTCH1. The exact sequence is proprietary.
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                                            亚型
- IgG
 
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                                            应用备注
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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                                            说明
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                        Positive Control: H1299 
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                                            限制
- 仅限研究用
 
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    - 
                                            状态
- Liquid
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                                            浓度
- 0.85 mg/mL
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                                            缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
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                                            储存液
- Thimerosal (Merthiolate)
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                                            注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            储存条件
- 4 °C,-20 °C
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                                            储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
 
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    - Patched 1 (PTCH1)
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                                            别名
- patched 1
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                                            背景
- Patched 1 , BCNS , NBCCS , PTC , PTC1 , PTCH,This gene encodes a member of the patched gene family. The encoded protein is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis, as well as the desert hedgehog and indian hedgehog proteins. This gene functions as a tumor suppressor. Mutations of this gene have been associated with basal cell nevus syndrome, esophageal squamous cell carcinoma, trichoepitheliomas, transitional cell carcinomas of the bladder, as well as holoprosencephaly. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences and biological validity cannot be determined currently. [provided by RefSeq]
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                                            分子量
- 161 kDa
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                                            基因ID
- 5727
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                                            UniProt
- Q13635
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                                            途径
- Hedgehog Signaling, Carbohydrate Homeostasis, Tube Formation
 抗原
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