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Patched 1 抗体 (C-Term)

This anti-Patched 1 antibody is a 兔 多克隆 antibody detecting Patched 1 in WB. Suitable for 人.
产品编号 ABIN7465681
发货至: 中国

Quick Overview for Patched 1 抗体 (C-Term) (ABIN7465681)

抗原

See all Patched 1 (PTCH1) 抗体
Patched 1 (PTCH1)

适用

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  • 1
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宿主

  • 37
  • 7
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克隆类型

  • 42
  • 6
多克隆

标记

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This Patched 1 antibody is un-conjugated

应用范围

  • 34
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  • 1
Western Blotting (WB)
  • 抗原表位

    • 5
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    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    C-Term

    交叉反应

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human PTCH1. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: H1299

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.85 mg/mL

    缓冲液

    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    Patched 1 (PTCH1)

    别名

    patched 1

    背景

    Patched 1 , BCNS , NBCCS , PTC , PTC1 , PTCH,This gene encodes a member of the patched gene family. The encoded protein is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis, as well as the desert hedgehog and indian hedgehog proteins. This gene functions as a tumor suppressor. Mutations of this gene have been associated with basal cell nevus syndrome, esophageal squamous cell carcinoma, trichoepitheliomas, transitional cell carcinomas of the bladder, as well as holoprosencephaly. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences and biological validity cannot be determined currently. [provided by RefSeq]

    分子量

    161 kDa

    基因ID

    5727

    UniProt

    Q13635

    途径

    Hedgehog Signaling, Carbohydrate Homeostasis, Tube Formation
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