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Lamin B2 抗体

The 小鼠 单克隆 anti-Lamin B2 antibody (Clone GT144) (ABIN7464965) specifically detects Lamin B2 in WB, IF, ICC, IHC (p) 和 IP. The antibody is reactive with 人 samples.
产品编号 ABIN7464965
发货至: 中国
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Quick Overview for Lamin B2 抗体 (ABIN7464965)

抗原

See all Lamin B2 (LMNB2) 抗体
Lamin B2 (LMNB2)

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Lamin B2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)

质量等级

KO Validated

克隆位点

GT144
  • 交叉反应

    纯化方法

    Affinity purified by Protein G.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human Lamin B2. The exact sequence is proprietary.

    亚型

    IgG2a
  • 应用备注

    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: U87-MG , SK-N-SH , IMR32 , SK-N-AS , HepG2 , HepG2 nuclear

    Validation: KO/KD, Orthogonal

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.81 mg/mL

    缓冲液

    PBS, No Preservative

    储存液

    Without preservative

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    Lamin B2 (LMNB2)

    别名

    lamin B2

    背景

    Lamin B2 , EPM9 , LAMB2 , LMN2,The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B2. This gene is in a head-to-tail orientation with the gene for the translocase of inner mitochondrial membrane 13 homolog gene. [provided by RefSeq]

    分子量

    68 kDa

    基因ID

    84823

    UniProt

    Q03252

    途径

    Apoptosis, Caspase Cascade in Apoptosis
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