TDG 抗体 (N-Term)
Quick Overview for TDG 抗体 (N-Term) (ABIN7464910)
抗原
See all TDG 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- N-Term
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交叉反应
- 人, 大鼠
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the N-terminus region of human TDG. The exact sequence is proprietary.
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亚型
- IgG
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anti-Thymine-DNA Glycosylase (TDG) (AA 141-410) antibody
TDG 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Thymine-DNA Glycosylase (TDG) (AA 1-410) antibodyTDG 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Thymine-DNA Glycosylase (TDG) (Internal Region) antibodyTDG 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Thymine-DNA Glycosylase (TDG) antibodyTDG 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Thymine-DNA Glycosylase (TDG) (AA 1-410) antibodyTDG 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Thymine-DNA Glycosylase (TDG) antibodyTDG 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Thymine-DNA Glycosylase (TDG) (AA 281-310), (C-Term) antibodyTDG 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB19894 unconjugated
anti-Thymine-DNA Glycosylase (TDG) (AA 81-110), (N-Term) antibodyTDG 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal RB19893 unconjugated
anti-Thymine-DNA Glycosylase (TDG) (Center) antibodyTDG 适用: 人, 小鼠, 大鼠, Cow WB, IF, IC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:5000-1:20000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: rat brain , HeLa , TDG-transfected 293T
Validation: KO/KD, Overexpression
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- TDG (Thymine-DNA Glycosylase (TDG))
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别名
- thymine DNA glycosylase
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背景
- Thymine DNA glycosylase , hTDG,The protein encoded by this gene belongs to the TDG/mug DNA glycosylase family. Thymine-DNA glycosylase (TDG) removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mispaired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine. This gene may have a pseudogene in the p arm of chromosome 12. [provided by RefSeq]
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分子量
- 46 kDa
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基因ID
- 6996
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UniProt
- Q13569
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途径
- DNA Damage Repair, Chromatin Binding
抗原
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