PARN 抗体
Quick Overview for PARN 抗体 (ABIN7464840)
抗原
See all PARN 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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特异性
- Knockdown/Knockout validation was supported by references (PMID:26990993)
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交叉反应
- 人, 小鼠
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human PARN. The exact sequence is proprietary.
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亚型
- IgG
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anti-Poly A Specific Ribonuclease (PARN) (AA 1-639) antibody
PARN 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Poly A Specific Ribonuclease (PARN) (AA 1-639) antibodyPARN 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Poly A Specific Ribonuclease (PARN) antibodyPARN 适用: 人, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Poly A Specific Ribonuclease (PARN) (AA 1-301) antibodyPARN 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC, FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Poly A Specific Ribonuclease (PARN) (AA 501-599) antibodyPARN 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Poly A Specific Ribonuclease (PARN) antibodyPARN 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Poly A Specific Ribonuclease (PARN) (AA 1-280) antibodyPARN 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Poly A Specific Ribonuclease (PARN) antibodyPARN 适用: 人 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Poly A Specific Ribonuclease (PARN) antibodyPARN 适用: 人, 小鼠, 大鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Poly A Specific Ribonuclease (PARN) (N-Term) antibodyPARN 适用: 人, 小鼠, 大鼠, Cow, 犬, 猴, 豚鼠, 马, 兔, Bat, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: NIH-3T3 , BCL-1
Validation: KO/KD
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- PARN (Poly A Specific Ribonuclease (PARN))
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别名
- poly(A)-specific ribonuclease
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背景
- Poly(A)-specific ribonuclease , DAN , DKCB6 , PFBMFT4,The protein encoded by this gene is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mRNAs. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs. This protein is also involved in silencing of certain maternal mRNAs during oocyte maturation and early embryonic development, as well as in nonsense-mediated decay (NMD) of mRNAs that contain premature stop codons. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
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分子量
- 73 kDa
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基因ID
- 5073
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UniProt
- O95453
抗原
-
