电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

Estrogen Receptor alpha 抗体 (AA 1-190)

This 小鼠 单克隆 antibody specifically detects Estrogen Receptor alpha in WB, FACS, IP 和 IHC (fro). It exhibits reactivity toward 人.
产品编号 ABIN7464705
发货至: 中国
Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Estrogen Receptor alpha 抗体 (AA 1-190) (ABIN7464705)

抗原

See all Estrogen Receptor alpha (ESR1) 抗体
Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))

适用

  • 571
  • 186
  • 176
  • 19
  • 18
  • 14
  • 10
  • 7
  • 7
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1

宿主

  • 418
  • 162
  • 1
小鼠

克隆类型

  • 360
  • 222
  • 1
单克隆

标记

  • 238
  • 41
  • 21
  • 18
  • 15
  • 12
  • 12
  • 12
  • 12
  • 12
  • 12
  • 11
  • 11
  • 11
  • 11
  • 11
  • 11
  • 10
  • 8
  • 8
  • 8
  • 8
  • 8
  • 8
  • 8
  • 8
  • 8
  • 8
  • 8
  • 7
  • 3
  • 3
  • 1
This Estrogen Receptor alpha antibody is un-conjugated

应用范围

  • 403
  • 203
  • 179
  • 161
  • 121
  • 94
  • 80
  • 56
  • 56
  • 53
  • 32
  • 28
  • 21
  • 15
  • 7
  • 7
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

1F3
  • 抗原表位

    • 34
    • 33
    • 32
    • 30
    • 30
    • 29
    • 28
    • 16
    • 16
    • 16
    • 16
    • 16
    • 15
    • 15
    • 13
    • 11
    • 11
    • 9
    • 9
    • 9
    • 8
    • 7
    • 7
    • 7
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    AA 1-190

    特异性

    This antibody is specific for ER alpha protein, and it does not cross react with ER beta protein.

    交叉反应

    人, 兔

    纯化方法

    Protein G purified

    免疫原

    The region encoding amino acids 1-190 expressed in E. coli.

    亚型

    IgG1
  • 应用备注

    WB: 1:500-1:3000. IP: 1 - 5 μg/mL. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: MCF-7 , DDDDK-tagged ESR1-transfected 293T

    Validation: Comparison, Orthogonal, Overexpression

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.56 mg/mL

    缓冲液

    PBS, No Preservative

    储存液

    Without preservative

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))

    别名

    estrogen receptor 1

    背景

    Estrogen receptor 1 , ER , ESR , ESRA , ESTRR , Era , NR3A1,This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined. [provided by RefSeq, Mar 2014]

    分子量

    66 kDa

    基因ID

    2099

    UniProt

    P03372

    途径

    Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
You are here: