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EPAS1 抗体

This 小鼠 单克隆 antibody specifically detects EPAS1 in WB, ICC, IP 和 IF. It exhibits reactivity toward 人.
产品编号 ABIN7464570
发货至: 中国
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北京 101111
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for EPAS1 抗体 (ABIN7464570)

抗原

See all EPAS1 抗体
EPAS1 (Endothelial PAS Domain Protein 1 (EPAS1))

适用

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宿主

  • 108
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小鼠

克隆类型

  • 91
  • 26
单克隆

标记

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This EPAS1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunocytochemistry (ICC), Immunoprecipitation (IP), Immunofluorescence (IF)

克隆位点

GT125
  • 交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Affinity purified by Protein G.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human HIF2 alpha. The exact sequence is proprietary.

    亚型

    IgG1
  • 应用备注

    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IP: 1:100-1:700. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: HepG2 (1% O2 treatment for 24hr)

    Validation: Orthogonal

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1XPBS pH 7, 20 % Glycerol, No preservative

    储存液

    Without preservative

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    EPAS1 (Endothelial PAS Domain Protein 1 (EPAS1))

    别名

    endothelial PAS domain protein 1

    背景

    Endothelial PAS domain protein 1 , ECYT4 , HIF2A , HLF , MOP2 , PASD2 , bHLHe73,This gene encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The encoded protein contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in this gene are associated with erythrocytosis familial type 4. [provided by RefSeq, Nov 2009]

    分子量

    96 kDa

    基因ID

    2034

    UniProt

    Q99814

    途径

    Signaling Events mediated by VEGFR1 and VEGFR2, Warburg Effect
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