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PKC theta 抗体 (pSer695)

This 兔 多克隆 anti-PKC theta antibody specifically detects PKC theta in WB. The antibody is reactive with 人 samples.
产品编号 ABIN7464464
发货至: 中国
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Quick Overview for PKC theta 抗体 (pSer695) (ABIN7464464)

抗原

See all PKC theta (PRKCQ) 抗体
PKC theta (PRKCQ) (Protein Kinase C, theta (PRKCQ))

适用

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宿主

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克隆类型

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多克隆

标记

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This PKC theta antibody is un-conjugated

应用范围

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Western Blotting (WB)
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    pSer695

    交叉反应

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Carrier-protein conjugated synthetic peptide surrounding phospho Ser695 of human PKC theta. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: HeLa , HepG2 , Molt-4 , MCF7 (500nM PMA treatment for 1hr)

    Validation: Orthogonal

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.66 mg/mL

    缓冲液

    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    PKC theta (PRKCQ) (Protein Kinase C, theta (PRKCQ))

    别名

    protein kinase C theta

    背景

    Protein kinase C theta , PRKCT , nPKC-theta,Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipid-dependent protein kinase. This kinase is important for T-cell activation. It is required for the activation of the transcription factors NF-kappaB and AP-1, and may link the T cell receptor (TCR) signaling complex to the activation of the transcription factors. [provided by RefSeq]

    分子量

    82 kDa

    基因ID

    5588

    UniProt

    Q04759

    途径

    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Thromboxane A2 Receptor Signaling
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