Nibrin 抗体
Quick Overview for Nibrin 抗体 (ABIN7464244)
抗原
See all Nibrin (NBN) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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交叉反应
- 人, 小鼠
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纯化方法
- Protein G purified
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免疫原
- The complete coding region of the human p95/NBS1 expressed in E. coli.
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亚型
- IgG1
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应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: 293T , MCF7 , HeLa , Raji
Validation: KO/KD, Orthogonal
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, No Preservative
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储存液
- Without preservative
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Nibrin (NBN)
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别名
- nibrin
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背景
- Nibrin , AT-V1 , AT-V2 , ATV , NBS , NBS1 , P95,Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. [provided by RefSeq, Jul 2008]
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分子量
- 85 kDa
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基因ID
- 4683
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UniProt
- O60934
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途径
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
抗原
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