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Nibrin 抗体

The 小鼠 单克隆 anti-Nibrin antibody is suitable to detect Nibrin in samples from 人. It has been validated for WB, IF, ICC 和 IP.
产品编号 ABIN7464244
发货至: 中国
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Quick Overview for Nibrin 抗体 (ABIN7464244)

抗原

See all Nibrin (NBN) 抗体
Nibrin (NBN)

适用

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宿主

  • 136
  • 15
小鼠

克隆类型

  • 96
  • 55
单克隆

标记

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This Nibrin antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunoprecipitation (IP)

质量等级

KO Validated

克隆位点

1C3
  • 交叉反应

    人, 小鼠

    纯化方法

    Protein G purified

    免疫原

    The complete coding region of the human p95/NBS1 expressed in E. coli.

    亚型

    IgG1
  • 应用备注

    WB: 1:500-1:3000. ICC/IF: 1:100. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: 293T , MCF7 , HeLa , Raji

    Validation: KO/KD, Orthogonal

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1XPBS ( pH 7), 20 % Glycerol, No Preservative

    储存液

    Without preservative

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    Nibrin (NBN)

    别名

    nibrin

    背景

    Nibrin , AT-V1 , AT-V2 , ATV , NBS , NBS1 , P95,Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. [provided by RefSeq, Jul 2008]

    分子量

    85 kDa

    基因ID

    4683

    UniProt

    O60934

    途径

    DNA Damage Repair, Production of Molecular Mediator of Immune Response
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