HMGA1 抗体 (N-Term)
Quick Overview for HMGA1 抗体 (N-Term) (ABIN7464188)
抗原
See all HMGA1 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
-
-
抗原表位
- N-Term
-
交叉反应
- 人
-
纯化方法
- Purified by antigen-affinity chromatography.
-
免疫原
- Recombinant protein encompassing a sequence within the N-terminus region of human HMGA1. The exact sequence is proprietary.
-
亚型
- IgG
-
-
-
-
应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
-
说明
-
Positive Control: 293T , A431 , HeLa , HepG2
Validation: KO/KD
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.87 mg/mL
-
缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
-
-
- HMGA1 (High Mobility Group AT-Hook 1 (HMGA1))
-
别名
- high mobility group AT-hook 1
-
背景
- High mobility group AT-hook 1 , HMG-R , HMGA1A , HMGIY,This gene encodes a non-histone protein involved in many cellular processes, including regulation of inducible gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of A+T-rich regions in double-stranded DNA. It has little secondary structure in solution but assumes distinct conformations when bound to substrates such as DNA or other proteins. The encoded protein is frequently acetylated and is found in the nucleus. At least seven transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq]
-
分子量
- 12 kDa
-
基因ID
- 3159
-
UniProt
- P17096
-
途径
- Nuclear Hormone Receptor Binding, Autophagy
抗原
-