TIM3 抗体
Quick Overview for TIM3 抗体 (ABIN7457966)
抗原
See all TIM3 (TIM 3) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- Purified
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亚型
- IgG2a, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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Matching Isotype Control: Purified Rat IgG2a, κ Isotype Control (ABIN7469837)
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS with 0.05 % Proclin300
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 2~8°C. Do not freeze.
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- TIM3 (TIM 3) (Hepatitis A Virus Cellular Receptor 2 (TIM 3))
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别名
- CD366/Tim-3
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物质类
- Virus
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背景
- TIM3, TIMD3,HAVcr-2,TIMD-3,CD366 (Tim-3) is a transmembrane protein also known as T cell immunoglobulin and mucin domain containing protein-3. Tim-3 is expressed at high levels on activated T cells (preferentially on Th1 cells, monocytes/macrophages, and dendritic cells). Tim-3 has also been shown to exist as a soluble protein. Cells expressing Tim-3 are present at high levels in the CNS of animals at the onset of experimental autoimmune encephalomyelitis (EAE), a disease mediated by lymphocytes secreting Th1-like cytokines. Tim-3 has been proposed to inhibit Th1-mediated immune responses and promote immunological tolerance.
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基因ID
- 84868
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UniProt
- Q8VIM0
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途径
- Regulation of Lipid Metabolism by PPARalpha, Cancer Immune Checkpoints
抗原
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