CCR3 抗体 (PE-Cy5)
Quick Overview for CCR3 抗体 (PE-Cy5) (ABIN7457335)
抗原
See all CCR3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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亚型
- IgG2b, kappa
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应用备注
- The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
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说明
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Matching Isotype Control: PE/Cyanine5 Mouse IgG2b, κ Isotype Control[MPC-11] (ABIN7469797)
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限制
- 仅限研究用
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缓冲液
- PBS with 0.05 % Proclin300, 1 % Protein protectant
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
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- CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))
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别名
- CD193
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背景
- CC CKR3, MIP1-alpha receptor like-2, eotaxin receptor,CCR,C-C chemokine receptor type 3,CD193, also known as CC-chemokine receptor 3 (CCR3), CC CKR3, MIP1-alpha receptor like-2, and eotaxin receptor, is a member of the G protein-coupled seven transmembrane receptors family. It binds to the CC chemokines eotaxin, eotaxin-2, and eotaxin-3 with high affinity. CCR3 has also been reported to bind RANTES, MCP-3, and MCP-4 with low affinity. CCR3 receptor is expressed on human eosinophils, basophils, mast cells, mononuclear phagocytes, platelets, CD34+ hematopoietic progenitor cells, Th2-like lymphocytes, and keratinocytes. CCR3 is thought to play a role in allergic diseases such as bronchial asthma and allergic rhinitis. CCR3 is a co-receptor for HIV-1 and HIV-2, and the binding of eotaxin with CCR3 has been shown to inhibit HIV infection in some cell types.
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基因ID
- 1232
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UniProt
- P51677
抗原
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