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CD51 抗体 (PE)

This anti-CD51 antibody is a 大鼠 单克隆 antibody detecting CD51 in FACS. Suitable for 小鼠.
产品编号 ABIN7457171
发货至: 中国

Quick Overview for CD51 抗体 (PE) (ABIN7457171)

抗原

See all CD51 (ITGAV) 抗体
CD51 (ITGAV) (Integrin alpha V (ITGAV))

适用

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小鼠

宿主

  • 75
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大鼠

克隆类型

  • 86
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单克隆

标记

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This CD51 antibody is conjugated to PE

应用范围

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Flow Cytometry (FACS)

克隆位点

RMV-7
  • 亚型

    IgG1, kappa
  • 应用备注

    Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10^6 cells in 100 μL volume].

    说明

    Matching Isotype Control: PE Rat IgG1, κ Isotype Control (ABIN7469822)

    限制

    仅限研究用
  • 浓度

    0.2 mg/mL

    缓冲液

    PBS with 0.05 % Proclin300, 1 % BSA

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
  • 抗原

    CD51 (ITGAV) (Integrin alpha V (ITGAV))

    别名

    CD51

    背景

    Integrin alpha-V,αV integrin,Vitronectin Receptor,Integrin αV chain,ITGAV,CD51 is a 140 kD protein, also known as αV integrin, vitronectin receptor, and integrin αV. It is a member of the integrin family, expressed on activated T cells, polymorphonuclear granulocytes, platelets, blastocysts, and osteoclasts. CD51 forms heterodimers by association with integrins β1, β3, β5 or β6, these complexes then act as receptors for multiple extracellular matrix proteins (ECM). The αvintegrin heterodimers have varied functions in development, stimulation/activation and homeostasis. The primary ligands for CD51 complexes are fibronectin, fibrinogen, vitronectin, thrombspondin, von Willebrand factor, and CD31. The RMV-7 antibody has been reported to block binding of CD51 to vitronectin, fibronectin, and CD31 in some cell types, as well as blocking LAK cell cytotoxicity.

    基因ID

    16410

    UniProt

    P43406

    途径

    Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Integrin Complex
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