CD40 抗体 (Biotin)
Quick Overview for CD40 抗体 (Biotin) (ABIN7456693)
抗原
See all CD40 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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亚型
- IgG1, kappa
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应用备注
- For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10^6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
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说明
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Matching Isotype Control: Biotin Mouse IgG1, κ Isotype Control[MOPC-21] (ABIN7469769)
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS with 0.05 % Proclin300, 1 % Protein protectant
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 2~8°C. Do not freeze.
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- CD40
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别名
- CD40
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背景
- Bp50,CDw40,CD40L receptor,TNFRSF5,CD40 is a 48 kD type I glycoprotein also known as BP50. It is a member of the TNFR superfamily primarily expressed on B cells, macrophages, follicular dendritic cells, endothelial cells, fibroblasts, and at low levels on plasma cells. CD40 has been reported to be involved in B cell differentiation, costimulation, isotype class-switching, and protection of B cells from apoptosis. Additionally, CD40 is important for T cell-B cell interactions. The ligand of CD40 is CD154 (CD40 ligand).
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基因ID
- 958
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UniProt
- P25942
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途径
- NF-kappaB Signaling, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
抗原
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