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CD40 抗体 (Biotin)

This anti-CD40 antibody is a 大鼠 单克隆 antibody detecting CD40 in FACS. Suitable for 小鼠.
产品编号 ABIN7456631
发货至: 中国

Quick Overview for CD40 抗体 (Biotin) (ABIN7456631)

抗原

See all CD40 抗体
CD40

适用

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小鼠

宿主

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大鼠

克隆类型

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单克隆

标记

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This CD40 antibody is conjugated to Biotin

应用范围

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Flow Cytometry (FACS)

克隆位点

FGK4-5-FGK45
  • 亚型

    IgG2a, kappa
  • 应用备注

    For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10^6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

    说明

    Matching Isotype Control: Biotin Rat IgG2a, κ Isotype Control (ABIN7469838)

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    PBS with 0.05 % Proclin300, 1 % BSA

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 2~8°C. Do not freeze.
  • 抗原

    CD40

    别名

    CD40

    背景

    Tumor necrosis factor receptor superfamily member 5,Cd40,B-cell surface antigen CD40,Bp50,CD40L receptor,CD40,Tnfrsf5,CD40 is a 48 kD type I transmembrane glycoprotein also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154 (gp39), which is expressed on activated T cells, is important in costimulation and immune regulation.

    基因ID

    21939

    UniProt

    P27512

    途径

    NF-kappaB Signaling, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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