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CD40 抗体 (APC)

This anti-CD40 antibody is a 大鼠 单克隆 antibody detecting CD40 in FACS. Suitable for 小鼠.
产品编号 ABIN7456387
发货至: 中国

Quick Overview for CD40 抗体 (APC) (ABIN7456387)

抗原

See all CD40 抗体
CD40

适用

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小鼠

宿主

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大鼠

克隆类型

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单克隆

标记

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This CD40 antibody is conjugated to APC

应用范围

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Flow Cytometry (FACS)

克隆位点

FGK4-5-FGK45
  • 亚型

    IgG2a, kappa
  • 应用备注

    Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10^6 cells in 100 μL volume].

    说明

    Matching Isotype Control: APC Rat IgG2a, κ Isotype Control (ABIN7469841)

    限制

    仅限研究用
  • 浓度

    0.2 mg/mL

    缓冲液

    PBS with 0.05 % Proclin300, 1 % BSA

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
  • 抗原

    CD40

    别名

    CD40

    背景

    Tumor necrosis factor receptor superfamily member 5,Cd40,B-cell surface antigen CD40,Bp50,CD40L receptor,CD40,Tnfrsf5,CD40 is a 48 kD type I transmembrane glycoprotein also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154 (gp39), which is expressed on activated T cells, is important in costimulation and immune regulation.

    基因ID

    21939

    UniProt

    P27512

    途径

    NF-kappaB Signaling, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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