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SIGLEC7 抗体

This anti-SIGLEC7 antibody is a 兔 Chimeric antibody detecting SIGLEC7 in FACS. Suitable for 人.
产品编号 ABIN7490814
发货至: 中国

Quick Overview for SIGLEC7 抗体 (ABIN7490814)

抗原

See all SIGLEC7 抗体
SIGLEC7 (Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7))

片段

Fc fragment

适用

  • 93
  • 11
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  • 1
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宿主

  • 63
  • 30
  • 1

克隆类型

  • 63
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  • 1
Chimeric

标记

  • 57
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  • 4
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  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This SIGLEC7 antibody is un-conjugated

应用范围

  • 72
  • 46
  • 37
  • 22
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  • 16
  • 9
  • 3
  • 2
  • 2
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  • 1
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Flow Cytometry (FACS)
  • 产品特性

    Rabbit/Human Fc chimeric IgG1

    纯化方法

    Purified from cell culture supernatant by affinity chromatography

    亚型

    IgG1
  • 应用备注

    Flow Cyt 1:100

    限制

    仅限研究用
  • 状态

    Liquid

    储存条件

    -20 °C,-80 °C

    储存方法

    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

    有效期

    12 months
  • 抗原

    SIGLEC7 (Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7))

    别名

    SIGLEC7

    背景

    AIRM-1, AIRM1, CD328, CDw328, D-siglec, p75, p75/AIRM1, QA79, SIGLEC-7, SIGLEC19P, SIGLECP2,
    Description: Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- and alpha-2,6-linked sialic acid. Also binds disialogangliosides (disialogalactosyl globoside, disialyl lactotetraosylceramide and disialyl GalNAc lactotetraoslylceramide). The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Mediates inhibition of natural killer cells cytotoxicity. May play a role in hemopoiesis. Inhibits differentiation of CD34 cell precursors towards myelomonocytic cell lineage and proliferation of leukemic myeloid cells (in vitro).[UniProtKB/Swiss-Prot Function]

    UniProt

    Q9Y286
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