Recombinant KLRK1 抗体
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Quick Overview for Recombinant KLRK1 抗体 (ABIN7490593)
抗原
See all KLRK1 抗体抗体类型
片段
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-NKG2D antibody(DMC287), IgG1 Chimeric mAb
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纯化方法
- Purified from cell culture supernatant by affinity chromatography
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亚型
- IgG1
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anti-Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) (AA 73-216) antibody
KLRK1 适用: 人, 大鼠 WB, FACS, ELISA 宿主: 小鼠 Monoclonal 5C9B4 unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) (AA 121-219) antibodyKLRK1 适用: 小鼠 WB, FACS, ELISA, IHC (fro), IF (cc), IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) antibody (FITC)KLRK1 适用: 人 FACS 宿主: 小鼠 Monoclonal 1D11 FITC
anti-Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) antibodyKLRK1 适用: 人 FACS, IP, IHC (fro) 宿主: 小鼠 Monoclonal 1D11 unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) antibodyKLRK1 适用: 人 FACS, IP, IHC (fro), Func 宿主: 小鼠 Monoclonal 1D11 unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) antibodyKLRK1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) (AA 73-216) antibodyKLRK1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) (AA 92-216) antibodyKLRK1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) (AA 90-232) antibodyKLRK1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) (AA 75-215) antibodyKLRK1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Flow Cyt 1:100
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please see Certificate of Analysis for specific instructions of reconstitution.
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缓冲液
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
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储存条件
- -20 °C,-80 °C
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储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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有效期
- 12 months
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- KLRK1 (Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1))
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别名
- NKG2D
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背景
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NKG2D,CD314,KLRK1,NK cell receptor D,
Description: ,Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed in NK cells. This gene encodes a member of the NKG2 family. The encoded transmembrane protein is characterized by a type II membrane orientation (has an extracellular C terminus) and the presence of a C-type lectin domain. It binds to a diverse family of ligands that include MHC class I chain-related A and B proteins and UL-16 binding proteins, where ligand-receptor interactions can result in the activation of NK and T cells. The surface expression of these ligands is important for the recognition of stressed cells by the immune system, and thus this protein and its ligands are therapeutic targets for the treatment of immune diseases and cancers. Read-through transcription exists between this gene and the upstream KLRC4 (killer cell lectin-like receptor subfamily C, member 4) family member in the same cluster. -
UniProt
- P26718
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途径
- Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
抗原
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