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KLRK1 抗体

KLRK1 适用: 人 FACS 宿主: 兔 Chimeric unconjugated Fc fragment
产品编号 ABIN7490593
发货至: 中国
  • 抗原 See all KLRK1 抗体
    KLRK1 (Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1))
    片段
    Fc fragment
    适用
    • 52
    • 36
    • 8
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    宿主
    • 59
    • 14
    • 5
    • 1
    • 1
    克隆类型
    • 57
    • 19
    • 3
    Chimeric
    标记
    • 38
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KLRK1 antibody is un-conjugated
    应用范围
    • 44
    • 35
    • 19
    • 16
    • 15
    • 13
    • 12
    • 10
    • 9
    • 6
    • 6
    • 5
    • 5
    • 5
    • 4
    Flow Cytometry (FACS)
    产品特性
    Rabbit/Human Fc chimeric IgG1
    纯化方法
    Purified from cell culture supernatant by affinity chromatography
    亚型
    IgG1
    Top Product
    Discover our top product KLRK1 Primary Antibody
  • 应用备注
    Flow Cyt  1:100
    限制
    仅限研究用
  • 状态
    Liquid
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    KLRK1 (Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1))
    别名
    NKG2D (KLRK1 产品)
    背景
    NKG2D,CD314,KLRK1,NK cell receptor D,
    Description: ,Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed in NK cells. This gene encodes a member of the NKG2 family. The encoded transmembrane protein is characterized by a type II membrane orientation (has an extracellular C terminus) and the presence of a C-type lectin domain. It binds to a diverse family of ligands that include MHC class I chain-related A and B proteins and UL-16 binding proteins, where ligand-receptor interactions can result in the activation of NK and T cells. The surface expression of these ligands is important for the recognition of stressed cells by the immune system, and thus this protein and its ligands are therapeutic targets for the treatment of immune diseases and cancers. Read-through transcription exists between this gene and the upstream KLRC4 (killer cell lectin-like receptor subfamily C, member 4) family member in the same cluster.
    UniProt
    P26718
    途径
    Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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