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RPA2 抗体 (pSer4, pSer8)

This anti-RPA2 antibody is a 兔 多克隆 antibody detecting RPA2 in WB, IP, IF/ICC 和 IHC (fp). Suitable for 人 和 小鼠.
产品编号 ABIN7455212
发货至: 中国

Quick Overview for RPA2 抗体 (pSer4, pSer8) (ABIN7455212)

抗原

See all RPA2 抗体
RPA2 (Replication Protein A2, 32kDa (RPA2))

适用

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  • 73
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  • 1
  • 1
人, 小鼠

宿主

  • 121
  • 29
  • 2
  • 1

克隆类型

  • 104
  • 49
多克隆

标记

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This RPA2 antibody is un-conjugated

应用范围

  • 126
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Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (fixed cells) (IF/ICC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
  • 抗原表位

    • 29
    • 15
    • 8
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    pSer4, pSer8

    原理

    Rabbit anti-Phospho RPA32 (S4/S8) Antibody, Affinity Purified

    预测反应

    Orangutan

    纯化方法

    Affinity Purified

    免疫原

    surrounding serine 4/8

    亚型

    IgG
  • 应用备注

    ICC-IF: 1:500 - 1:5,000

    IHC: 1:500 to 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: 2 - 10 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    限制

    仅限研究用
  • 浓度

    1000 μg/mL

    缓冲液

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    RPA2 (Replication Protein A2, 32kDa (RPA2))

    别名

    RPA32

    背景

    Background: Replication protein A (RPA) is a multisubunit complex that carries out DNA mismatch repair (MMR) in association with MSH2 (a subunit of human MutS heterodimers), MLH1 (a subunit of human MutL heterodimers), PCNA, and DNA polymerase-delta. RPA is composed of a heterotrimer that includes subunits of 70 kDa (RPA1), 32 kDa (RPA2), and 14 kDa (RPA3). RPA2, the 32 kDa subunit, is phosphorylated by the cdc2 family of kinases when cells enter S-phase and in response to DNA damage by ATM, ATR, and DNA-PK.

    基因ID

    6118

    NCBI登录号

    NP_002937

    UniProt

    P15927

    途径

    Telomere Maintenance, DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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