Recombinant BMI1 抗体 (AA 250-300)
Quick Overview for Recombinant BMI1 抗体 (AA 250-300) (ABIN7455106)
抗原
See all BMI1 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 250-300
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原理
- Rabbit anti-BMI1 Recombinant Monoclonal Antibody [BLR119H]
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免疫原
- between AA 250 and 300
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亚型
- IgG
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应用备注
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IHC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 6 μL/1 mg lysate
ICC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.
WB: 01:01,00
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Borate Buffered Saline (BBS) pH 8.2 with 0.09 % Sodium Azide, BSA-Free
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))
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别名
- BMI1
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背景
- Background: BMI1 (B lymphoma Mo-MLV insertion region 1 homolog) is a core component of the polycomb group (PcG) multiprotein PRC1 complex which plays an important role in transcriptional repression of gene expression during development. BMI1 association with RING protein 1B is important to the E3 ligase activity of RING1B in the PRC1 complex. BMI1 is an oncogene whose overexpression is associated with many types of human tumors and is a stem-cell marker and regulator of stem cell self-renewal.
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基因ID
- 648
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NCBI登录号
- NP_005171
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UniProt
- P35226
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途径
- Cell Division Cycle, Autophagy
抗原
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