电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

TDG 抗体 (AA 360-410)

This anti-TDG antibody is a 兔 多克隆 antibody detecting TDG in WB, IP 和 IHC (fp). Suitable for 人.
产品编号 ABIN7455026
发货至: 中国
Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for TDG 抗体 (AA 360-410) (ABIN7455026)

抗原

See all TDG 抗体
TDG (Thymine-DNA Glycosylase (TDG))

适用

  • 51
  • 20
  • 12
  • 2
  • 1

宿主

  • 39
  • 12

克隆类型

  • 42
  • 10
多克隆

标记

  • 45
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This TDG antibody is un-conjugated

应用范围

  • 40
  • 15
  • 13
  • 9
  • 6
  • 5
  • 3
  • 3
  • 3
  • 2
Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
  • 抗原表位

    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 360-410

    原理

    Rabbit anti-TDG Antibody, Affinity Purified

    纯化方法

    Affinity Purified

    免疫原

    Between AA 360 and 410

    亚型

    IgG
  • 应用备注

    IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: 2 - 10 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    限制

    仅限研究用
  • 浓度

    1000 μg/mL

    缓冲液

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    TDG (Thymine-DNA Glycosylase (TDG))

    别名

    TDG

    背景

    Background: Thymine-DNA glycosylase (TDG) removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mispaired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine [taken from NCBI Entrez Gene (Gene ID: 6996)].

    基因ID

    6996

    NCBI登录号

    NP_003202

    UniProt

    Q13569

    途径

    DNA Damage Repair, Chromatin Binding
You are here: